Polyethylene glycol-conjugated HER2-targeted peptides as a nuclear imaging probe for HER2-overexpressed gastric cancer detection in vivo

BACKGROUND: The human epidermal growth factor receptor 2 (HER2) involved proliferation, angiogenesis, and reduced apoptosis in gastric cancer (GC), which is a common target for tumor therapy. HER2 is usually overexpressed in more than 15% GC patients, developing a reliable diagnostic tool for tumor...

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Detalles Bibliográficos
Publicado en:J Transl Med
Main Authors: Guan, Siao-Syun, Wu, Cheng-Tien, Chiu, Chen-Yuan, Luo, Tsai-Yueh, Wu, Jeng-Yih, Liao, Tse-Zung, Liu, Shing-Hwa
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2018
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009821/
https://ncbi.nlm.nih.gov/pubmed/29921305
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12967-018-1550-3
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