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Emerin modulates spatial organization of chromosome territories in cells on softer matrices

Cells perceive and relay external mechanical forces into the nucleus through the nuclear envelope. Here we examined the effect of lowering substrate stiffness as a paradigm to address the impact of altered mechanical forces on nuclear structure-function relationships. RNA sequencing of cells on soft...

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Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Pradhan, Roopali, Ranade, Devika, Sengupta, Kundan
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009696/
https://ncbi.nlm.nih.gov/pubmed/29684168
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky288
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