StpA and Hha stimulate pausing by RNA polymerase by promoting DNA–DNA bridging of H-NS filaments

In enterobacteria, AT-rich horizontally acquired genes, including virulence genes, are silenced through the actions of at least three nucleoid-associated proteins (NAPs): H-NS, StpA and Hha. These proteins form gene-silencing nucleoprotein filaments through direct DNA binding by H-NS and StpA homodi...

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Vydáno v:Nucleic Acids Res
Hlavní autoři: Boudreau, Beth A, Hron, Daniel R, Qin, Liang, van der Valk, Ramon A, Kotlajich, Matthew V, Dame, Remus T, Landick, Robert
Médium: Artigo
Jazyk:Inglês
Vydáno: Oxford University Press 2018
Témata:
Gene regulation, Chromatin and Epigenetics
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009659/
https://ncbi.nlm.nih.gov/pubmed/29718386
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky265
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