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Modulation of 3-Hydroxy-3-methylglutaryl-CoA Reductase Gene Expression by CuZn Superoxide Dismutase in Human Fibroblasts and HepG2 Cells

The homeostasis of intracellular cholesterol in animal cells is highly regulated by a complex system in which the microsomal rate-limiting enzyme 3-hydroxy-3-methylglutaryl CoA (HMG-CoA) reductase plays a key role in cholesterol synthesis. Substantial evidence has demonstrated that the cytosolic ant...

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Detalhes bibliográficos
Publicado no:Gene Expr
Main Authors: De Felice, Bruna, Santillo, Mariarosaria, Serù, Rosalba, Damiano, Simona, Matrone, Gianfranco, Wilson, Robert Roy, Mondola, Paolo
Formato: Artigo
Idioma:Inglês
Publicado em: Cognizant Communication Corporation 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009104/
https://ncbi.nlm.nih.gov/pubmed/15473258
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