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The clinical potential of romosozumab for the prevention of fractures in postmenopausal women with osteoporosis
The glycoprotein sclerostin inhibits activation of the canonical Wnt pathway and thereby suppresses bone formation by inhibiting the osteoblasts. Additionally, sclerostin increases bone resorption by stimulating the production of receptor activator of nuclear factor kappa-β-ligand (RANKL). Romosozum...
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| 出版年: | Ther Adv Musculoskelet Dis |
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| 主要な著者: | , , |
| フォーマット: | Artigo |
| 言語: | Inglês |
| 出版事項: |
SAGE Publications
2018
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| 主題: | |
| オンライン･アクセス: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6009094/ https://ncbi.nlm.nih.gov/pubmed/29942362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1759720X18775936 |
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