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The clinical potential of romosozumab for the prevention of fractures in postmenopausal women with osteoporosis

The glycoprotein sclerostin inhibits activation of the canonical Wnt pathway and thereby suppresses bone formation by inhibiting the osteoblasts. Additionally, sclerostin increases bone resorption by stimulating the production of receptor activator of nuclear factor kappa-β-ligand (RANKL). Romosozum...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Ther Adv Musculoskelet Dis
Prif Awduron: Sølling, Anne Sophie Koldkjær, Harsløf, Torben, Langdahl, Bente
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: SAGE Publications 2018
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009094/
https://ncbi.nlm.nih.gov/pubmed/29942362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1759720X18775936
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