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The clinical potential of romosozumab for the prevention of fractures in postmenopausal women with osteoporosis
The glycoprotein sclerostin inhibits activation of the canonical Wnt pathway and thereby suppresses bone formation by inhibiting the osteoblasts. Additionally, sclerostin increases bone resorption by stimulating the production of receptor activator of nuclear factor kappa-β-ligand (RANKL). Romosozum...
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| Foilsithe in: | Ther Adv Musculoskelet Dis |
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| Main Authors: | , , |
| Formáid: | Artigo |
| Teanga: | Inglês |
| Foilsithe: |
SAGE Publications
2018
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| Ábhair: | |
| Rochtain Ar Líne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6009094/ https://ncbi.nlm.nih.gov/pubmed/29942362 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1759720X18775936 |
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