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The clinical potential of romosozumab for the prevention of fractures in postmenopausal women with osteoporosis

The glycoprotein sclerostin inhibits activation of the canonical Wnt pathway and thereby suppresses bone formation by inhibiting the osteoblasts. Additionally, sclerostin increases bone resorption by stimulating the production of receptor activator of nuclear factor kappa-β-ligand (RANKL). Romosozum...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:Ther Adv Musculoskelet Dis
Egile Nagusiak: Sølling, Anne Sophie Koldkjær, Harsløf, Torben, Langdahl, Bente
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: SAGE Publications 2018
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC6009094/
https://ncbi.nlm.nih.gov/pubmed/29942362
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1177/1759720X18775936
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