Phase I and II trial on infusional 5-fluorouracil and gefitinib in combination with preoperative radiotherapy in rectal cancer: 10-years median follow-up

PURPOSE: The aim of this study is to evaluate the long term survival of the addition of gefitinib to chemoradiotherapy (CRT) in locally advanced rectal cancer (LARC). METHODS AND MATERIALS: This previously published multicentre, open-label, phase I-II study, enrolled patients (pts) with LARC to rece...

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Pubblicato in:Clin Transl Radiat Oncol
Autori principali: Gambacorta, Maria Antonietta, De Paoli, Antonino, Lupattelli, Marco, Chiloiro, Giuditta, Solazzo, Angela Pia, Barbaro, Brunella, Alfieri, Sergio, Vecchio, Fabio Maria, Lenkowicz, Jacopo, Navarria, Francesco, Palazzari, Elisa, Bertola, Giulio, Frattegiani, Alessandro, Minsky, Bruce, Valentini, Vincenzo
Natura: Artigo
Lingua:Inglês
Pubblicazione: Elsevier 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008630/
https://ncbi.nlm.nih.gov/pubmed/29928702
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.ctro.2018.02.003
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