Andrographolide Inhibits Mechanical and Thermal Hyperalgesia in a Rat Model of HIV-Induced Neuropathic Pain

Aim: In this study, we investigated whether andrographolide (Andro) can alleviate neuropathic pain induced by HIV gp120 plus ddC treatment and the mechanism of its action. Methods: The paw withdrawal threshold and the paw withdrawal latency were observed to assess pain behaviors in all groups of the...

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Veröffentlicht in:Front Pharmacol
Hauptverfasser: Yi, Zhihua, Ouyang, Shuai, Zhou, Congfa, Xie, Lihui, Fang, Zhi, Yuan, Huilong, Yang, Jinpu, Zou, Lifang, Jia, Tianyu, Zhao, Shanhong, Li, Lin, Shi, Liran, Gao, Yun, Li, Guilin, Liu, Shuangmei, Xu, Hong, Xu, Changshui, Zhang, Chunping, Liang, Shangdong
Format: Artigo
Sprache:Inglês
Veröffentlicht: Frontiers Media S.A. 2018
Schlagworte:
Pharmacology
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008568/
https://ncbi.nlm.nih.gov/pubmed/29950989
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2018.00593
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