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Local and global influences on protein turnover in neurons and glia

Regulation of protein turnover allows cells to react to their environment and maintain homeostasis. Proteins can show different turnover rates in different tissue, but little is known about protein turnover in different brain cell types. We used dynamic SILAC to determine half-lives of over 5100 pro...

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Détails bibliographiques
Publié dans:eLife
Auteurs principaux: Dörrbaum, Aline R, Kochen, Lisa, Langer, Julian D, Schuman, Erin M
Format: Artigo
Langue:Inglês
Publié: eLife Sciences Publications, Ltd 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008053/
https://ncbi.nlm.nih.gov/pubmed/29914620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.34202
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