Lamellar projections in the endolymphatic sac act as a relief valve to regulate inner ear pressure

The inner ear is a fluid-filled closed-epithelial structure whose function requires maintenance of an internal hydrostatic pressure and fluid composition. The endolymphatic sac (ES) is a dead-end epithelial tube connected to the inner ear whose function is unclear. ES defects can cause distended ear...

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Detalhes bibliográficos
Publicado no:eLife
Main Authors: Swinburne, Ian A, Mosaliganti, Kishore R, Upadhyayula, Srigokul, Liu, Tsung-Li, Hildebrand, David G C, Tsai, Tony Y -C, Chen, Anzhi, Al-Obeidi, Ebaa, Fass, Anna K, Malhotra, Samir, Engert, Florian, Lichtman, Jeff W, Kirchhausen, Tomas, Betzig, Eric, Megason, Sean G
Formato: Artigo
Idioma:Inglês
Publicado em: eLife Sciences Publications, Ltd 2018
Assuntos:
Cell Biology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6008045/
https://ncbi.nlm.nih.gov/pubmed/29916365
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.37131
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