An intrinsic epigenetic barrier for functional axon regeneration

Mature neurons in the adult peripheral nervous system can effectively switch from a dormant state with little axonal growth to robust axon regeneration upon injury. The mechanisms by which injury unlocks mature neurons’ intrinsic axonal growth competence are not well understood. Here we show that pe...

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Udgivet i:Neuron
Main Authors: Weng, Yi-Lan, An, Ran, Cassin, Jessica, Joseph, Jessica, Mi, Ruifa, Wang, Chen, Zhong, Chun, Jin, Seung-Gi, Pfeifer, Gerd P., Bellacosa, Alfonso, Dong, Xinzhong, Hoke, Ahmet, He, Zhigang, Song, Hongjun, Ming, Guo-li
Format: Artigo
Sprog:Inglês
Udgivet: 2017
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007997/
https://ncbi.nlm.nih.gov/pubmed/28426967
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.neuron.2017.03.034
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