Dynamic Cellular Integration Drives Functional Assembly of the Heart’s Pacemaker Complex

Impulses generated by a multicellular, bioelectric signaling center termed the sinoatrial node (SAN) stimulate the rhythmic contraction of the heart. The SAN consists of a network of electrochemically oscillating pacemaker cells encased in a heterogeneous connective tissue microenvironment. Although...

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Pubblicato in:Cell Rep
Autori principali: Bressan, Michael, Henley, Trevor, Louie, Jonathan D., Liu, Gary, Christodoulou, Danos, Bai, Xue, Taylor, Joan, Seidman, Christine E., Seidman, J.G., Mikawa, Takashi
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007983/
https://ncbi.nlm.nih.gov/pubmed/29791840
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2018.04.075
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