Target amplicon exome-sequencing identifies promising diagnosis and prognostic markers involved in RTK-RAS and PI3K-AKT signaling as central oncopathways in primary central nervous system lymphoma

Exome-sequencing for somatic mutation detection and copy number variation analysis are effective and valid methods for evaluating human cancers in current molecular medicine. We conducted target amplicon exome-sequencing analyses using PCR target enrichment and next-generation sequencing on Ion Prot...

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Bibliographische Detailangaben
Veröffentlicht in:Oncotarget
Hauptverfasser: Takashima, Yasuo, Sasaki, Yasushi, Hayano, Azusa, Homma, Jumpei, Fukai, Junya, Iwadate, Yasuo, Kajiwara, Koji, Ishizawa, Shin, Hondoh, Hiroaki, Tokino, Takashi, Yamanaka, Ryuya
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2018
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007945/
https://ncbi.nlm.nih.gov/pubmed/29937999
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.25463
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