Effect of genetic background and delivery route on the preclinical properties of a live attenuated RSV vaccine

A safe and effective vaccine against RSV remains an important unmet public health need. Intranasally (IN) delivered live-attenuated vaccines represent the most extensively studied approach for immunization of RSV-naïve infants and children, however, achieving an effective balance of attenuation and...

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Bibliografiske detaljer
Udgivet i:PLoS One
Main Authors: Groppo, Rachel, DiNapoli, Joshua, Il Jeong, Kwang, Kishko, Michael, Jackson, Nicholas, Kleanthous, Harold, Delagrave, Simon, Zhang, Linong, Parrington, Mark
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2018
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007926/
https://ncbi.nlm.nih.gov/pubmed/29920563
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199452
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