The mitochondrial oxidoreductase CHCHD4 is present in a semi-oxidized state in vivo

Disulfide formation in the mitochondrial intermembrane space is an essential process catalyzed by a disulfide relay machinery. In mammalian cells, the key enzyme in this machinery is the oxidoreductase CHCHD4/Mia40. Here, we determined the in vivo CHCHD4 redox state, which is the major determinant o...

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Detalles Bibliográficos
Publicado en:Redox Biol
Main Authors: Erdogan, Alican J., Ali, Muna, Habich, Markus, Salscheider, Silja L., Schu, Laura, Petrungaro, Carmelina, Thomas, Luke W., Ashcroft, Margaret, Leichert, Lars I., Roma, Leticia Prates, Riemer, Jan
Formato: Artigo
Idioma:Inglês
Publicado: Elsevier 2018
Assuntos:
Short Communication
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007816/
https://ncbi.nlm.nih.gov/pubmed/29704824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.03.014
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