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Valproate serum concentrations in patients with hypoalbuminemia and medical complications

INTRODUCTION: Valproic acid (VPA) and its derivatives are highly protein bound with free fraction increasing with dose and serum concentration. Consensus guidelines regarding dose adjustment for hypoalbuminemia are not available. METHODS: A literature search was performed using PubMed to identify ar...

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Publicado en:Ment Health Clin
Main Authors: VandenBerg, Amy, Broadway, Jessica, Lalich, Callie, Kennedy, Rachel, Williams, Kristen
Formato: Artigo
Idioma:Inglês
Publicado: College of Psychiatric & Neurologic Pharmacists 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007656/
https://ncbi.nlm.nih.gov/pubmed/29955492
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.9740/mhc.2017.01.013
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