SUMOylation of the m(6)A-RNA methyltransferase METTL3 modulates its function

The methyltransferase like 3 (METTL3) is a key component of the large N(6)-adenosine-methyltransferase complex in mammalian responsible for N6-methyladenosine (m(6)A) modification in diverse RNAs including mRNA, tRNA, rRNA, small nuclear RNA, microRNA precursor and long non-coding RNA. However, the...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Du, Yuzhang, Hou, Guofang, Zhang, Hailong, Dou, Jinzhuo, He, Jianfeng, Guo, Yanming, Li, Lian, Chen, Ran, Wang, Yanli, Deng, Rong, Huang, Jian, Jiang, Bin, Xu, Ming, Cheng, Jinke, Chen, Guo-Qiang, Zhao, Xian, Yu, Jianxiu
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
RNA and RNA-protein complexes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007514/
https://ncbi.nlm.nih.gov/pubmed/29506078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky156
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