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Comparison of Dopamine D(3) and D(2) Receptor Occupancies by a Single Dose of Blonanserin in Healthy Subjects: A Positron Emission Tomography Study With [(11)C]-(+)-PHNO
BACKGROUND: Blockade of D(3) receptor, a member of the dopamine D(2)-like receptor family, has been suggested as a possible medication for schizophrenia. Blonanserin has high affinity in vitro for D(3) as well as D(2) receptors. We investigated whether a single dose of 12 mg blonanserin, which was w...
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Publicado no: | Int J Neuropsychopharmacol |
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Main Authors: | , , , , , , |
Formato: | Artigo |
Idioma: | Inglês |
Publicado em: |
Oxford University Press
2018
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Assuntos: | |
Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6007421/ https://ncbi.nlm.nih.gov/pubmed/29346639 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/ijnp/pyy004 |
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