The aberrant splicing of BAF45d links splicing regulation and transcription in glioblastoma

BACKGROUND: Glioblastoma, the most aggressive primary brain tumor, is genetically heterogeneous. Alternative splicing (AS) plays a key role in numerous pathologies, including cancer. The objectives of our study were to determine whether aberrant AS could play a role in the malignant phenotype of gli...

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Detalhes bibliográficos
Publicado no:Neuro Oncol
Main Authors: Aldave, Guillermo, Gonzalez-Huarriz, Marisol, Rubio, Angel, Romero, Juan Pablo, Ravi, Datta, Miñana, Belén, Cuadrado-Tejedor, Mar, García-Osta, Ana, Verhaak, Roeland, Xipell, Enric, Martinez-Vélez, Naiara, de la Rocha, Arlet Acanda, Puigdelloses, Montserrat, García-Moure, Marc, Marigil, Miguel, Gállego Pérez-Larraya, Jaime, Marín-Bejar, Oskar, Huarte, Maite, Carro, Maria Stella, Ferrarese, Roberto, Belda-Iniesta, Cristobal, Ayuso, Angel, Prat-Acín, Ricardo, Pastor, Fernando, Díez-Valle, Ricardo, Tejada, Sonia, Alonso, Marta M
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Basic and Translational Investigations
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007380/
https://ncbi.nlm.nih.gov/pubmed/29373718
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/neuonc/noy007
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