Drosophila tsRNAs preferentially suppress general translation machinery via antisense pairing and participate in cellular starvation response

Transfer RNA-derived small RNAs (tsRNAs) are an emerging class of small RNAs, yet their regulatory roles have not been well understood. Here we studied the molecular mechanisms and consequences of tsRNA-mediated regulation in Drosophila. By analyzing 495 public small RNA libraries, we demonstrate th...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Luo, Shiqi, He, Feng, Luo, Junjie, Dou, Shengqian, Wang, Yirong, Guo, Annan, Lu, Jian
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
RNA and RNA-protein complexes
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007262/
https://ncbi.nlm.nih.gov/pubmed/29548011
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky189
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