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High throughput discovery of protein variants using proteomics informed by transcriptomics

Proteomics informed by transcriptomics (PIT), in which proteomic MS/MS spectra are searched against open reading frames derived from de novo assembled transcripts, can reveal previously unknown translated genomic elements (TGEs). However, determining which TGEs are truly novel, which are variants of...

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Detalles Bibliográficos
Publicado en:Nucleic Acids Res
Main Authors: Saha, Shyamasree, Matthews, David A, Bessant, Conrad
Formato: Artigo
Idioma:Inglês
Publicado: Oxford University Press 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007231/
https://ncbi.nlm.nih.gov/pubmed/29718325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky295
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