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High throughput discovery of protein variants using proteomics informed by transcriptomics

Proteomics informed by transcriptomics (PIT), in which proteomic MS/MS spectra are searched against open reading frames derived from de novo assembled transcripts, can reveal previously unknown translated genomic elements (TGEs). However, determining which TGEs are truly novel, which are variants of...

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Detalhes bibliográficos
Publicado no:Nucleic Acids Res
Main Authors: Saha, Shyamasree, Matthews, David A, Bessant, Conrad
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007231/
https://ncbi.nlm.nih.gov/pubmed/29718325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gky295
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