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Integrative metabolomics and transcriptomics signatures of clinical tolerance to Plasmodium vivax reveal activation of innate cell immunity and T cell signaling

Almost invariably, humans become ill during primary infections with malaria parasites which is a pathology associated with oxidative stress and perturbations in metabolism. Importantly, repetitive exposure to Plasmodium results in asymptomatic infections, which is a condition defined as clinical tol...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Gardinassi, Luiz G., Arévalo-Herrera, Myriam, Herrera, Sócrates, Cordy, Regina J., Tran, ViLinh, Smith, Matthew R., Johnson, Michelle S., Chacko, Balu, Liu, Ken H., Darley-Usmar, Victor M., Go, Young-Mi, Jones, Dean P., Galinski, Mary R., Li, Shuzhao
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6007173/
https://ncbi.nlm.nih.gov/pubmed/29698924
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2018.04.011
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