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Effect of β-Eudesmol on NQO1 suppression-enhanced sensitivity of cholangiocarcinoma cells to chemotherapeutic agents

BACKGROUND: Cholangiocarcinoma (CCA), an epithelial malignancy of the biliary tree, is one of the aggressive cancers with poor prognosis and unsatisfactory response to chemotherapy with acquired resistance. NAD(P)H-quinone oxidoreductase 1 (NQO1), an antioxidant/detoxifying enzyme, plays important r...

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Détails bibliographiques
Publié dans:BMC Pharmacol Toxicol
Auteurs principaux: Srijiwangsa, Pimradasiri, Ponnikorn, Saranyoo, Na-Bangchang, Kesara
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2018
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006851/
https://ncbi.nlm.nih.gov/pubmed/29914576
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s40360-018-0223-4
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