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Elevated expression of hyaluronan synthase 2 associates with decreased survival in diffusely infiltrating astrocytomas

BACKGROUND: Diffusely infiltrating astrocytomas originate from astrocytic glial cells or their precursor cells and are the most common type of brain tumors in adults. In this retrospective study, we investigated the content of hyaluronan, its cell surface receptor, CD44 and the expression of hyaluro...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Valkonen, Mari, Haapasalo, Hannu, Rilla, Kirsi, Tyynelä-Korhonen, Kristiina, Soini, Ylermi, Pasonen-Seppänen, Sanna
Format: Artigo
Language:Inglês
Published: BioMed Central 2018
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006557/
https://ncbi.nlm.nih.gov/pubmed/29914429
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-018-4569-1
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