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CXCR1/Akt signaling activation induced by mesenchymal stem cell-derived IL-8 promotes osteosarcoma cell anoikis resistance and pulmonary metastasis

The loss of appropriate cell adhesion normally induces apoptosis via a process termed anoikis. The aim of this study was to investigate the effects of mesenchymal stem cells (MSCs) in the cancer microenvironment on the anoikis resistance and pulmonary metastasis of osteosarcoma (OS) cells, and to ev...

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書目詳細資料
發表在:Cell Death Dis
Main Authors: Du, Lin, Han, Xiu-guo, Tu, Bing, Wang, Min-qi, Qiao, Han, Zhang, Shu-hong, Fan, Qi-ming, Tang, Ting-ting
格式: Artigo
語言:Inglês
出版: Nature Publishing Group UK 2018
主題:
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006172/
https://ncbi.nlm.nih.gov/pubmed/29915309
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-018-0745-0
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