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Next-generation sequencing for identifying genetic mutations in adults with bronchiectasis

BACKGROUND: Defective airway host-defense (e.g., altered mucus properties, ciliary defects) contributes to the pathogenesis of bronchiectasis. This study aims to determine whether genetic mutations associated with defective airway host-defense are implicated in the pathogenesis of bronchiectasis. ME...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:J Thorac Dis
Hauptverfasser: Guan, Wei-Jie, Li, Jia-Cheng, Liu, Fang, Zhou, Jian, Liu, Ya-Ping, Ling, Chao, Gao, Yong-Hua, Li, Hui-Min, Yuan, Jing-Jing, Huang, Yan, Chen, Chun-Lan, Chen, Rong-Chang, Zhang, Xue, Zhong, Nan-Shan
Format: Artigo
Sprache:Inglês
Veröffentlicht: AME Publishing Company 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6006054/
https://ncbi.nlm.nih.gov/pubmed/29997923
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.21037/jtd.2018.04.134
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