Biochemical Properties of Human D-amino Acid Oxidase Variants and Their Potential Significance in Pathologies

The stereoselective flavoenzyme D-amino acid oxidase (DAAO) catalyzes the oxidative deamination of neutral and polar D-amino acids producing the corresponding α-keto acids, ammonia, and hydrogen peroxide. Despite its peculiar and atypical substrates, DAAO is widespread expressed in most eukaryotic o...

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Bibliographic Details
Published in:Front Mol Biosci
Main Authors: Sacchi, Silvia, Cappelletti, Pamela, Murtas, Giulia
Format: Artigo
Language:Inglês
Published: Frontiers Media S.A. 2018
Subjects:
Molecular Biosciences
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005901/
https://ncbi.nlm.nih.gov/pubmed/29946548
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmolb.2018.00055
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