The BCGΔBCG1419c Vaccine Candidate Reduces Lung Pathology, IL-6, TNF-α, and IL-10 During Chronic TB Infection

Mycobacterium tuberculosis (M. tuberculosis), the causative agent of human tuberculosis (TB), is estimated to be harbored by up to 2 billion people in a latent TB infection (LTBI) state. The only TB vaccine approved for use in humans, BCG, does not confer protection against establishment of or react...

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Dettagli Bibliografici
Pubblicato in:Front Microbiol
Autori principali: Flores-Valdez, Mario A., Pedroza-Roldán, César, Aceves-Sánchez, Michel de Jesús, Peterson, Eliza J. R., Baliga, Nitin S., Hernández-Pando, Rogelio, Troudt, JoLynn, Creissen, Elizabeth, Izzo, Linda, Bielefeldt-Ohmann, Helle, Bickett, Thomas, Izzo, Angelo A.
Natura: Artigo
Lingua:Inglês
Pubblicazione: Frontiers Media S.A. 2018
Soggetti:
Microbiology
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005825/
https://ncbi.nlm.nih.gov/pubmed/29946316
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fmicb.2018.01281
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