Autosomal dominant cerebellar ataxias: Imaging biomarkers with high effect sizes

OBJECTIVE: As gene-based therapies may soon arise for patients with spinocerebellar ataxia (SCA), there is a critical need to identify biomarkers of disease progression with effect sizes greater than clinical scores, enabling trials with smaller sample sizes. METHODS: We enrolled a unique cohort of...

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Vydáno v:Neuroimage Clin
Hlavní autoři: Adanyeguh, Isaac M., Perlbarg, Vincent, Henry, Pierre-Gilles, Rinaldi, Daisy, Petit, Elodie, Valabregue, Romain, Brice, Alexis, Durr, Alexandra, Mochel, Fanny
Médium: Artigo
Jazyk:Inglês
Vydáno: Elsevier 2018
Témata:
Regular Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005808/
https://ncbi.nlm.nih.gov/pubmed/29922574
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nicl.2018.06.011
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