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HIV-1 gp120 Upregulates Brain-Derived Neurotrophic Factor (BDNF) Expression in BV2 Cells via the Wnt/β-Catenin Signaling Pathway

HIV-1 gp120 plays a critical role in the pathogenesis of HIV-associated pain, but the underlying molecular mechanisms are incompletely understood. This study aims to determine the effect and possible mechanism of HIV-1 gp120 on BDNF expression in BV2 cells (a murine-derived microglial cell line). We...

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Detalhes bibliográficos
Publicado no:J Mol Neurosci
Main Authors: Wang, Yongdi, Liao, Jinxu, Tang, Shao-Jun, Shu, Jianhong, Zhang, Wenping
Formato: Artigo
Idioma:Inglês
Publicado em: 2017
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005692/
https://ncbi.nlm.nih.gov/pubmed/28560687
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s12031-017-0931-z
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