Fuchs' Endothelial Corneal Dystrophy in Patients With Myotonic Dystrophy, Type 1

PURPOSE: RNA toxicity from CTG trinucleotide repeat (TNR) expansion within noncoding DNA of the transcription factor 4 (TCF4) and DM1 protein kinase (DMPK) genes has been described in Fuchs' endothelial corneal dystrophy (FECD) and myotonic dystrophy, type 1 (DM1), respectively. We prospectivel...

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Detalhes bibliográficos
Publicado no:Invest Ophthalmol Vis Sci
Main Authors: Winkler, Nelson S., Milone, Margherita, Martinez-Thompson, Jennifer M., Raja, Harish, Aleff, Ross A., Patel, Sanjay V., Fautsch, Michael P., Wieben, Eric D., Baratz, Keith H.
Formato: Artigo
Idioma:Inglês
Publicado em: The Association for Research in Vision and Ophthalmology 2018
Assuntos:
Cornea
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005624/
https://ncbi.nlm.nih.gov/pubmed/30025114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1167/iovs.17-23160
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