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The effects of the selective muscarinic M3 receptor antagonist darifenacin, and of hyoscine (scopolamine), on motion sickness, skin conductance & cognitive function

AIMS: The aim of this study was to compare the effects of the selective M3 muscarinic acetylcholine receptor antagonist darifenacin, oral hyoscine hydrobromide and placebo on motion sickness induced by cross‐coupled stimulation. METHODS: The effects of darifenacin 10 mg or 20 mg, hyoscine hydrobromi...

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Detalles Bibliográficos
Publicado en:Br J Clin Pharmacol
Main Authors: Golding, John F., Wesnes, Keith A., Leaker, Brian R.
Formato: Artigo
Idioma:Inglês
Publicado: John Wiley and Sons Inc. 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005615/
https://ncbi.nlm.nih.gov/pubmed/29522648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/bcp.13579
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