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Reconstitution and functional studies of hamster P-glycoprotein in giant liposomes

This paper describes the preparation of giant unilamellar vesicles with reconstituted hamster P-glycoprotein (Pgp, ABCB1) for studying the transport activity of this efflux pump in individual liposomes using optical microscopy. Pgp, a member of ABC (ATP-binding cassette) transporter family, is known...

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Detalles Bibliográficos
Publicado en:PLoS One
Main Authors: Park, SooHyun, Majd, Sheereen
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2018
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005519/
https://ncbi.nlm.nih.gov/pubmed/29912971
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0199279
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