Disruption of protein kinase A localization induces acrosomal exocytosis in capacitated mouse sperm

Protein kinase A (PKA) is a broad-spectrum Ser/Thr kinase involved in the regulation of several cellular activities. Thus, its precise activation relies on being localized at specific subcellular places known as discrete PKA signalosomes. A-Kinase anchoring proteins (AKAPs) form scaffolding assembli...

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Publicado en:J Biol Chem
Autores principales: Stival, Cintia, Ritagliati, Carla, Xu, Xinran, Gervasi, Maria G., Luque, Guillermina M., Baró Graf, Carolina, De la Vega-Beltrán, José Luis, Torres, Nicolas, Darszon, Alberto, Krapf, Diego, Buffone, Mariano G., Visconti, Pablo E., Krapf, Dario
Formato: Artigo
Lenguaje:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2018
Materias:
Cell Biology
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005427/
https://ncbi.nlm.nih.gov/pubmed/29700114
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.002286
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