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Bromoethylindole (BEI-9) redirects NF-κB signaling induced by camptothecin and TNFα to promote cell death in colon cancer cells

Chemotherapeutic regimens containing camptothecin (CPT), 5-fluorouracil, and oxaliplatin are used to treat advanced colorectal cancer. We previously reported that an indole derivative, 3-(2-bromoethyl)indole (BEI-9), inhibited the proliferation of colon cancer cells and suppressed NF-κB activation....

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Dettagli Bibliografici
Pubblicato in:Apoptosis
Autori principali: Chowdhury, Rupak, Gales, Dominique, Valenzuela, Paloma, Miller, Sonni, Yehualaeshet, Teshome, Manne, Upender, Francia, Giulio, Samuel, Temesgen
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2017
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005376/
https://ncbi.nlm.nih.gov/pubmed/29116428
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s10495-017-1427-6
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