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Genomic evidence that the live Chlamydia abortus vaccine strain 1B is not attenuated and has the potential to cause disease
BACKGROUND: The live, temperature-attenuated vaccine strain 1B of Chlamydia abortus, the aetiological agent of ovine enzootic abortion (OEA), has been implicated in cases of vaccine breakdown. The aim of this study was to understand the nature of this attenuation through sequencing of the vaccine pa...
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| Udgivet i: | Vaccine |
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| Main Authors: | , , , , , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Elsevier Science
2018
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6005232/ https://ncbi.nlm.nih.gov/pubmed/29759381 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2018.05.042 |
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