Fiber-mediated nourishment of gut microbiota protects against diet-induced obesity by restoring IL-22-mediated colonic health

Dietary supplementation with fermentable fiber suppresses adiposity and the associated parameters of metabolic syndrome. Microbiota-generated fiber-derived short-chain fatty acids (SCFA) and free fatty acid receptors including GPR43 are thought to mediate these effects. We find that while fermentabl...

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Bibliographic Details
Published in:Cell Host Microbe
Main Authors: Zou, Jun, Chassaing, Benoit, Singh, Vishal, Pellizzon, Michael, Ricci, Matthew, Fythe, Michael, Kumar, Matam Vijay, Gewirtz, Andrew T.
Format: Artigo
Language:Inglês
Published: 2017
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005180/
https://ncbi.nlm.nih.gov/pubmed/29276170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.chom.2017.11.003
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