Safety and immunogenicity of a Vi-DT typhoid conjugate vaccine: Phase I trial in Healthy Filipino adults and children

BACKGROUND: Typhoid fever remains a major public health problem in low- and middle-income countries where children aged 2–14 years bear the greatest burden. Vi polysaccharide is poorly immunogenic in children <2 years of age, and protection in adults is modest. The limitations of Vi polysaccharid...

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Publicado no:Vaccine
Main Authors: Capeding, Maria Rosario, Teshome, Samuel, Saluja, Tarun, Syed, Khalid Ali, Kim, Deok Ryun, Park, Ju Yeon, Yang, Jae Seung, Kim, Yang Hee, Park, Jiwook, Jo, Sue-Kyoung, Chon, Yun, Kothari, Sudeep, Yang, Seon-Young, Ham, Dong Soo, Ryu, Ji Hwa, Hwang, Hee-Seong, Mun, Ju-Hwan, Lynch, Julia A., Kim, Jerome H., Kim, Hun, Excler, Jean-Louis, Sahastrabuddhe, Sushant
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier Science 2018
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005168/
https://ncbi.nlm.nih.gov/pubmed/29776750
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.vaccine.2018.05.038
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