Association of Pneumococcal Protein Antigen Serology With Age and Antigenic Profile of Colonizing Isolates

BACKGROUND: Several Streptococcus pneumoniae proteins play a role in pathogenesis and are being investigated as vaccine targets. It is largely unknown whether naturally acquired antibodies reduce the risk of colonization with strains expressing a particular antigenic variant. METHODS: Serum immunogl...

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Detalhes bibliográficos
Publicado no:J Infect Dis
Main Authors: Azarian, Taj, Grant, Lindsay R, Georgieva, Maria, Hammitt, Laura L, Reid, Raymond, Bentley, Stephen D, Goldblatt, David, Santosham, Mathuran, Weatherholtz, Robert, Burbidge, Paula, Goklish, Novalene, Thompson, Claudette M, Hanage, William P, O’Brien, Kate L, Lipsitch, Marc
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2017
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Major Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6005115/
https://ncbi.nlm.nih.gov/pubmed/28035010
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/infdis/jiw628
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