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LRSAM1 Depletion Affects Neuroblastoma SH-SY5Y Cell Growth and Morphology: The LRSAM1 c.2047-1G>A Loss-of-Function Variant Fails to Rescue The Phenotype

OBJECTIVE: Deleterious variants in LRSAM1, a RING finger ubiquitin ligase which is also known as TSG101-associated ligase (TAL), have recently been associated with Charcot-Marie-Tooth disease type 2P (CMT2P). The mechanism by which mutant LRSAM1 contributes to the development of neuropathy is curren...

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Detalles Bibliográficos
Publicado en:Cell J
Main Authors: Minaidou, Anna, Nicolaou, Paschalis, Christodoulou, Kyproula
Formato: Artigo
Idioma:Inglês
Publicado: Royan Institute 2018
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004992/
https://ncbi.nlm.nih.gov/pubmed/29845787
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.22074/cellj.2018.5352
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