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PI3K/AKT inhibition induces compensatory activation of the MET/STAT3 pathway in non-small cell lung cancer

Constitutive activation of the phosphoinositide 3-kinase (PI3K)/AKT signaling pathway is evident in a diverse array of human cancer types, and targeting the pathway is an attractive therapeutic approach. However, pre-clinical and clinical studies have demonstrated that the antitumor efficacy of a nu...

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Detalhes bibliográficos
Publicado no:Oncol Lett
Main Authors: Bian, Chunan, Liu, Zonghang, Li, Dakou, Zhen, Lifeng
Formato: Artigo
Idioma:Inglês
Publicado em: D.A. Spandidos 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004714/
https://ncbi.nlm.nih.gov/pubmed/29928341
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8587
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