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Retinoic acid-metabolizing enzyme cytochrome P450 26A1 promotes skin carcinogenesis induced by 7,12-dimethylbenz[a]anthracene

Elevated expression of the retinoic acid-metabolizing enzyme cytochrome P450 26A1 (CYP26A1) has been demonstrated to have an oncogenic function in carcinogenesis. In order to address the oncogenic capacity of CYP26A1 in vivo, transgenic mice that ubiquitously overexpressed CYP26A1 driven by the cyto...

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Bibliographische Detailangaben
Veröffentlicht in:Oncol Lett
Hauptverfasser: Osanai, Makoto, Takasawa, Akira, Takasawa, Kumi, Murata, Masaki, Sawada, Norimasa
Format: Artigo
Sprache:Inglês
Veröffentlicht: D.A. Spandidos 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004672/
https://ncbi.nlm.nih.gov/pubmed/29928370
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3892/ol.2018.8599
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