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DNA binding by the MATα2 transcription factor controls its access to alternative ubiquitin-modification pathways

Like many transcription factors, the yeast protein MATalpha2 (α2) undergoes rapid proteolysis via the ubiquitin-proteasome system (UPS). At least two ubiquitylation pathways regulate α2 degradation: one pathway utilizes the ubiquitin ligase (E3) Doa10 and the other the heterodimeric E3 Slx5/Slx8. Do...

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Bibliografiske detaljer
Udgivet i:Mol Biol Cell
Main Authors: Hickey, Christopher M., Xie, Yang, Hochstrasser, Mark
Format: Artigo
Sprog:Inglês
Udgivet: The American Society for Cell Biology 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004586/
https://ncbi.nlm.nih.gov/pubmed/29298839
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-10-0589
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