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The neuron-specific formin Delphilin nucleates nonmuscle actin but does not enhance elongation

The formin Delphilin binds the glutamate receptor, GluRδ2, in dendritic spines of Purkinje cells. Both proteins play a role in learning. To understand how Delphilin functions in neurons, we studied the actin assembly properties of this formin. Formins have a conserved formin homology 2 domain, which...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Veröffentlicht in:Mol Biol Cell
Hauptverfasser: Silkworth, William T., Kunes, Kristina L., Nickel, Grace C., Phillips, Martin L., Quinlan, Margot E., Vizcarra, Christina L.
Format: Artigo
Sprache:Inglês
Veröffentlicht: The American Society for Cell Biology 2018
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004577/
https://ncbi.nlm.nih.gov/pubmed/29282276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E17-06-0363
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