Synthesis of Thymoquinone–Artemisinin Hybrids: New Potent Antileukemia, Antiviral, and Antimalarial Agents

[Image: see text] A series of hybrid compounds based on the natural products artemisinin and thymoquinone was synthesized and investigated for their biological activity against the malaria parasite Plasmodium falciparum 3D7 strain, human cytomegalovirus (HCMV), and two leukemia cell lines (drug-sens...

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Publicado en:ACS Med Chem Lett
Main Authors: Fröhlich, Tony, Reiter, Christoph, Saeed, Mohamed E. M., Hutterer, Corina, Hahn, Friedrich, Leidenberger, Maria, Friedrich, Oliver, Kappes, Barbara, Marschall, Manfred, Efferth, Thomas, Tsogoeva, Svetlana B.
Formato: Artigo
Idioma:Inglês
Publicado: American Chemical Society 2017
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004568/
https://ncbi.nlm.nih.gov/pubmed/29937978
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsmedchemlett.7b00412
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