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Lipids hide or step aside for CD1-autoreactive T cell receptors

Peptide and lipid antigens are presented to T cells when bound to MHC or CD1 proteins, respectively. The general paradigm of T cell antigen recognition is that T cell receptors (TCRs) co-recognize an epitope comprised of the antigen and antigen presenting molecule. Here we review the latest studies...

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Bibliografiske detaljer
Udgivet i:Curr Opin Immunol
Main Authors: Cotton, Rachel N., Shahine, Adam, Rossjohn, Jamie, Moody, D. Branch
Format: Artigo
Sprog:Inglês
Udgivet: 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004262/
https://ncbi.nlm.nih.gov/pubmed/29738961
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.coi.2018.04.013
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