Deptor is a novel target of Wnt/β-catenin/c-Myc and contributes to colorectal cancer cell growth

Activation of the Wnt/β-catenin signaling pathway drives colorectal cancer (CRC) growth by deregulating expression of downstream target genes including the c-Myc proto-oncogene. The critical targets that mediate the functions of oncogenic c-Myc in CRC have yet to be fully elucidated. Previously, we...

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Pubblicato in:Cancer Res
Autori principali: Wang, Qingding, Zhou, Yuning, Rychahou, Piotr, Harris, Jennifer W., Zaytseva, Yekaterina Y., Liu, Jinpeng, Wang, Chi, Weiss, Heidi L., Liu, Chunming, Lee, Eun Y., Evers, B. Mark
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004255/
https://ncbi.nlm.nih.gov/pubmed/29666061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/0008-5472.CAN-17-3107
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