Hydrogen peroxide is a neuronal alarmin that triggers specific RNAs, local translation of Annexin A2, and cytoskeletal remodeling in Schwann cells

Schwann cells are key players in neuro-regeneration: They sense “alarm” signals released by degenerating nerve terminals and differentiate toward a proregenerative phenotype, with phagocytosis of nerve debris and nerve guidance. At the murine neuromuscular junction, hydrogen peroxide (H(2)O(2)) is a...

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Veröffentlicht in:RNA
Hauptverfasser: Negro, Samuele, Stazi, Marco, Marchioretto, Marta, Tebaldi, Toma, Rodella, Umberto, Duregotti, Elisa, Gerke, Volker, Quattrone, Alessandro, Montecucco, Cesare, Rigoni, Michela, Viero, Gabriella
Format: Artigo
Sprache:Inglês
Veröffentlicht: Cold Spring Harbor Laboratory Press 2018
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Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6004060/
https://ncbi.nlm.nih.gov/pubmed/29643068
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1261/rna.064816.117
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