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Transmission-clearance trade-offs indicate that dengue virulence evolution depends on epidemiological context

An extensive body of theory addresses the topic of pathogen virulence evolution, yet few studies have empirically demonstrated the presence of fitness trade-offs that would select for intermediate virulence. Here we show the presence of transmission-clearance trade-offs in dengue virus using viremia...

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Detalhes bibliográficos
Publicado no:Nat Commun
Main Authors: Ben-Shachar, Rotem, Koelle, Katia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2018
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003961/
https://ncbi.nlm.nih.gov/pubmed/29907741
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-04595-w
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