Attenuation of inflammatory responses by (+)-syringaresinol via MAP-Kinase-mediated suppression of NF-κB signaling in vitro and in vivo

We examined the anti-inflammatory effects of (+)-syringaresinol (SGRS), a lignan isolated from Rubia philippinensis, in lipopolysaccharide (LPS)-stimulated RAW 264.7 cells using enzyme-based immuno assay, Western blotting, and RT-PCR analyses. Additionally, in vivo effects of SGRS in the acute infla...

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Publicat a:Sci Rep
Autors principals: Bajpai, Vivek K., Alam, Md Badrul, Quan, Khong Trong, Ju, Mi-Kyoung, Majumder, Rajib, Shukla, Shruti, Huh, Yun Suk, Na, MinKyun, Lee, Sang Han, Han, Young-Kyu
Format: Artigo
Idioma:Inglês
Publicat: Nature Publishing Group UK 2018
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003921/
https://ncbi.nlm.nih.gov/pubmed/29907781
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-018-27585-w
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