Allelic Variant in the Glucagon-Like Peptide 1 Receptor Gene Associated with Greater Effect of Liraglutide and Exenatide on Gastric Emptying: A Pilot Pharmacogenetics Study

BACKGROUND: Weight loss in response to the long-acting GLP-1 receptor (GLP1R) analog, liraglutide, is correlated with delay in gastric emptying (GE). The aim of this pilot study was to assess whether specific genetic variants in GLP1R or TCF7L2 are associated with delayed GE and weight loss in obese...

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Pubblicato in:Neurogastroenterol Motil
Autori principali: Chedid, Victor, Vijayvargiya, Priya, Carlson, Paula, Van Malderen, Kathleen, Acosta, Andres, Zinsmeister, Alan, Camilleri, Michael
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2018
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6003833/
https://ncbi.nlm.nih.gov/pubmed/29488276
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/nmo.13313
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